See also: Neuropathy (Nerve Damage) and HIV, PML – Progressive Multifocal Leukoencephalopathy, Toxoplasmosis

General Information

• Neurological complications of AIDS. (National Institutes of Health)
• Neurological & Neurocognitive Complications of HIV/AIDS – Web page on TheBody with links to many articles and fact sheets
• Depression and HIV (AIDS InfoNet) and Spanish version
• Nervous System Problems and Dementia (AIDS InfoNet) and Spanish version
• AIDS dementia complex Project Inform)
• AIDS Dementia Complex (ADC) (Poz)

Guidelines

• Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents (CDC, National Institutes of Health, and HIV Medicine Association of the Infectious Diseases Society of America)

Selected Recent Articles

• Rate of Tivicay’s Central Nervous System Side Effects Is Greater Than in Trials.  (December 2016, Poz)
• Cognitive function in young people with and without perinatal HIV in the AALPHI cohort in England: the role of non-HIV related factors.  (September 2016, Healio)
• Many Factors – From Marijuana to Heart Disease – Tied to Mental Slowing With HIV.  (September 2016, HIV Treatment Alerts/TheBodyPro)
• Meningitis Outbreak Strikes Gay and Bi Men in Southern California.  (September 2016, Poz)
• Three Non-AIDS Illnesses Tied to Cognitive Impairment in Men with HIV.  (September 2016, TheBodyPro)
• Elevated lipids associated with cognitive decline in middle-aged HIV-positive men doing well on ART.  (August 2016, AIDSmap)
• VACS IndeElevated lipids associated with cognitive decline in middle-aged HIV-positive men doing well on ART.  (August 2016, AIDSmap)x score can help identify HIV-positive people most at risk of neurocognitive decline.  (July 2016, AIDSmap)
• How does HIV change our brains?  (May 2016, Beta Blog)
• For the First Time, Alzheimer’s Is Diagnosed in Someone with HIV. (April 2016, Poz); related coverage from MedPage Today
• Antidepressant modestly improves HIV-related cognitive impairment (March 2016, AIDSmap); related coverage from Poz
• HIV-related factors increase risk of stroke.  (March 2016, AIDSmap)
• HIV in the brain – new tools and treatment options to keep your mind beautiful.  (February 2016, AIDSmap)
• Strokes, TIA more common among female, black HIV patients.  (February 2016, Healio)
• Various Factors Are Tied to Cognitive Impairment in People with HIV.  (February 2016, Poz)
• Broad range of risk factors associated with mild cognitive impairment in HIV-positive men on ART.  (February 2016, AIDSmap)
• Treating HIV Immediately May Protect Against Cognitive Decline.  (January 2016, Poz)
• Hepatitis C virus linked to increased risk of Parkinson’s disease, studies show.  (January 2016, AIDSmap)
• Malawian study provides strong evidence that HIV infection is an important risk factor for stroke.  (January 2016, AIDSmap)
• START sub-studies show no differences in lung or neurocognitive function with early or later treatment.  (October 2015, AIDSmap)
• HIV-Related Asymptomatic Cognitive Impairment Likely Progresses.  (October 2015, Poz)
• Asymptomatic neurocognitive impairment in people with HIV does predict later neurocognitive symptoms.  (September 2015, AIDSmap)
• HAND may be related to cerebrovascular risk factors in older patients with HIV.  (June 2015, Healio)
• A New, More Reliable Way to Gauge HIV-Related Cognitive Dysfunction.  (May 2015, Poz)
• Early HIV Replication in the Brain Supports Hasty Treatment Start.  (April 2015, Poz)
• The impact of physical activity on cognition in men with and without HIV.  (March 2015, NATAP)
• Aerobic Exercise Attenuates Cognitive Decline and Brain Volume Loss Associated With HIV.  (March 2015, NATAP)
• Hepatitis C infection and Cognition in Older HIV+ Adults.  (March 2015, NATAP)
• Poor kidney function predicts neurocognitive decline with undetectable viral load.  (February 2015, NATAP)
• Early antiretroviral treatment reduces seizure risk by two-thirds for children with HIV.  (February 2015, AIDSmap)
• Antiretroviral Neurotoxicity May Cause Cognitive Problems.  (January 2015, TheBodyPro)
• Hep C Doesn’t Apparently Lead to Cognitive Decline in People With HIV.  (December 2014, Poz)
• Lower CNS Side Effects, Similar Efficacy for Doravirine Vs. Sustiva.  (November 2014, Poz)
• Switch from efavirenz to rilpivirine quells CNS toxicity, improves sleep.  (September/October 2014, HIV Treatment Bulletin)
• Greater Clarity to How HIV May Lead to Cognitive Decline.  (September 2014, Poz)
• New Meningitis Cases Found in HIV-Positive Gay and Bi Men in NYC.  (September 2014, Poz)
• How Might Efavirenz Affect the Brain? (August/September 2014, CATIE)
• HIV, if Treated, May Not Raise Cognitive Impairment Risk.  (August 2014, Poz)
• People With HIV Appear to Have a Lower Risk of MS.  (August 2014, Poz)
• No Link Between Efavirenz and Neurocognitive Impairment in Italian Study.  (July 2014, Beta Blog)
• Efavirenz use not linked to neurocognitive impairment.  (July 2014, AIDSmap)
• Sustiva (Efavirenz) Linked to Doubled Risk of Suicidality.  (July 2014, Poz)
• Study finds no evidence that HIV-positive gay men in UK have increased risk of neurocognitive impairment.  (July 2014, AIDSmap)
• High CD4s Neutralize Raised Risk of Stroke in People With HIV.  (June 2014, Poz)
• Cardiovascular Risks Need Better Management In HIV Population.  (May 2014, Poz)
• PI Regimens Tied to Cerebral Small Vessel Disease – and CSVD Tied to HAND. (March 2014, NATAP)
• Brain Markers of Inflammation Drop to Normal With Early ART. (March 2014, NATAP)
• Study identifies factors associated with mortality in HIV-positive people with cryptococcal meningitis.  (January 2014, AIDSmap)
• Neurocognitive Impairment Tests Often Miss Milder Cases.  (October 2013, Poz)
• People’s friends diagnose brain impairment better than they do themselves.  (October 2013, AIDSmap)
• Switching from Atripla to Eviplera reduces central nervous system side-effects.  (September 2013, AIDSmap)
• Depression linked to episodes of detectable HIV in cerebrospinal fluid.  (September 2013, AIDSmap)