General Information

• Drug Interactions (AIDS InfoNet) and Spanish version
• Drug Interactions (Project Inform) – fact sheet with links to sites that allow you to check medications for possible interactions
• Database of Antiretroviral Drug Interactions (HIV InSite)
• HIV Drug Interactions – web site with tools that allow you to check interactions between HIV drugs and other medications and street drugs
• Drug Interactions:  A Comprehensive Listing of Potential Drug Interactions  (Positively Aware)
• Be an Active Member of Your Health Care Team – U.S. Food and Drug Administration fact sheet that includes guidance on taking medications properly

Selected Recent Articles

• Epclusa demonstrates manageable drug interaction profile with commonly used ART.  (September 2016, Healio)
• Sofosbuvir/velpatasvir for hepatitis C can be administered with most antiretrovirals (March 2016, AIDSmap); related coverage from Poz
• Taking Many Non-HIV Meds Is Linked to Shifts, Gaps in HIV Treatment.  (February 2016, Poz)
• Hep C Drugs Pose Risk of Drug-Drug Interactions.  (December 2015, Hepmag)
• Hepatitis C Treatment and Drug Interactions.  (November 2015, Hepmag)
• HIV-treatment ‘booster drugs’ are most likely to have dangerous interactions with methamphetamine, mephedrone, MDMA and ketamine.  (August 2015, AIDSmap)
• Harvoni and Sovaldi/Daclatasvir Safer to Mix With HIV Meds.  (June 2015, Poz)
• HIV Is Linked to Getting a Buzz on Less Alcohol.  (April 2015, Poz)
• Sovaldi or Harvoni and Heart Med Cordarone Can Be a Fatal Mix.  (March 2015, Hepmag)
• Contraceptive implant levorongestrel may not be as effective when taking efavirenz (Sustiva)  (March 2015, Project Inform)
• Coinfected People With Hep C May Have to Switch HIV Meds to Take Olysio.  (March 2015, Poz)
• Patients with HIV/HCV may require ART switch to receive Olysio.  (February 2015, Healio)
• Efavirenz decreases exposure to hormonal contraceptive implant.  (November-December 2014, HIV Treatment Bulletin)
• Sovaldi-Ledipasvir Pill Safe With Major HIV Meds.  (September 2014, Hepmag)
• AbbVie’s Hep C Regimen Is Safe with Opioid Replacement Therapy.  (July 2014, Hepmag)
• Gilead’s Sovaldi-Ledipasvir Pill Safe With Major HIV Drugs.  (May 2014, Poz)
• Ritonavir the cause of the interaction between telaprevir and ritonavir-boosted atazanavir.  (November 2013, AIDSmap)
• Simultaneous HIV and tuberculosis therapy doesn’t cause problems with liver function.  (October 2013, AIDSmap)
• New NNRTI MK-1439 interacts with ritonavir but not tenofovir.  (September 2013, AIDSmap)
• Steroid Injections Mixed With PIs Threaten Cortisol Levels.  (July 2013, Poz)
• Interaction between steroid injections and HIV protease inhibitors can disrupt cortisol levels.  (June 2013, AIDSmap)
• Updated Opportunistic Infection Guidelines Add Info on IRIS, Hepatitis, Drug Interactions.  (May 2013, HIVandhepatitis)
• Atripla Label Adds Interactions with Hepatitis C Drugs Boceprevir and Telaprevir.  (April 2013, HIVandhepatitis)
• Concentrations of HIV protease inhibitors increase with age.  (April 2013, AIDSmap)
• FDA Releases Updated Drug Interaction Information for Kaletra.  (February 2013, Poz)
• Kaletra Label Updated to Add Drug Interactions, Including Boceprevir and Telaprevir.  (January 2013, HIVandhepatitis)
• Combined oral contraception has less effect on nevirapine than efavirenz levels.  (December 2012, AIDSmap)
• Certain Meds Mixed With Grapefruit Juice Can Be a Fatal Cocktail.  (December 2012, Poz)
• Mixed Messages on Meds and Booze.  (December 2012, Poz)
• High-Dose Vitamins Don’t Fight HIV and Can Raise Liver Levels.  (November 2012, Poz)
• No Interactions Seen Between New TB Drug and Population HIV Meds. (August 2012, HIVandhepatitis)
• Co-administration of rifampicin and efavirenz does not reduce efavirenz concentrations or efficacy. (July 2012, AIDSmap)
• FDA to Docs: Best to Avoid Victrelis With Norvir-Boosted HIV Protease Inhibitors. (April 2012 by Poz)
• Studies look at interactions between new hepatitis C drugs and HIV antiretrovirals. (March 2012, AIDSmap)
• FDA updates guidance for use of HIV and hepatitis C protease inhibitors with statins. (March 2012, AIDSmap)
• Cholesterol-Reducing Statins, Other Meds to Be Avoided With Hep C Protease Inhibitors. (March 2012, Poz)
• Hep C, HIV Drug-Drug Interaction Studies Must Be a Priority, Activists Say. (February 2012, Poz)
• Merck Warns of Victrelis and HIV Protease Inhibitor Interactions. (February 2012, Poz)
• Guidelines published on management of interactions between anti-epileptic and anti-HIV drugs. (January 2012, AIDSmap)
• New Guidelines: Anti-Seizure Drug Selection for People Living With HIV. (January 2012, Poz)