See also: New and Experimental HIV Drugs and Treatments
Note: Salvage treatment is sometimes also called “Rescue Therapy” or “Third-Line Therapy.”
General Information
- Salvage Therapy (AIDS InfoNet) and Spanish version
- Is My Treatment Regimen Working? (AIDSInfo)
- HIV Treatment Failure (AIDSInfo)
- Management of the Treatment-Experienced Patient: Virologic Failure (from the U.S. Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents)
- Changing an HIV Treatment Regimen (AIDSInfo)
- Third Line/Rescue HIV Treatment (TheBody) – web page with links to fact sheets and articles
Selected Recent Articles
- Patients who fail modern HIV regimens show high prevalence of older mutations. (December 2016, Hepmag)
- Most patients taking second-line ART in sub-Saharan Africa achieve viral suppression but there’s a need for third-line treatment options. (August 2016, AIDSmap)
- Integrase Inhibitors Work Well to Treat NNRTI Drug Resistant HIV. (July 2016, Beta Blog)
- It’s OK for HIV Salvage Regimens to Nix Nukes. (January 2016, Poz)
- HIV salvage regimens can safely omit NRTIs, says US study. (January 2016, AIDSmap)
- Costs Spike for 2nd- and 3rd-Line ARVs and Late Treatment. (September 2013, Poz)
- New integrase inhibitor dolutegravir helps treatment-experienced people on failing therapy. (March 2013, AIDSmap)
- Can people with resistant HIV omit NRTIs when switching from a failing regimen? (March 2013, AIDSmap)
- HIV Meds Can Still Benefit Those with Triple-Class Failure. (January 2013, Poz)
- Australian researchers project that many HIV-positive people will run out of treatment options. (January 2013, AIDSmap)
- Any reduction in viral load has immunologic benefits for people with HIV who have triple-class treatment failure. (January 2013, AIDSmap)